October 20, 2006, Newsletter Issue #45: Estrogen Replacement Not Advisable For Osteoporosis, Heart Disease:
Tip of the Week
Osteoporosis is very common in Caucasian women, less so among other races. About a quarter of white women over sixty have compression fractures of their vertebrae, and many develop hip fractures due to the gradual loss of bone. But, estrogens are not nearly as good at protecting the bones as women may be led to believe, and they rarely arrest bone loss. At best, estrogens simply slow the rate of bone deterioration.
Because estrogen has a rate limiting effect on Osteoclasts, Estrogen Dominance delays the breakdown of bone tissue but does not support bone building (osteoblast function). Natural progesterone, on the other hand, stimulates osteoblast bone cell activity which results in new bone tissue growth. Consequently, estrogens only slow down bone loss, not promote the formation of new bone tissue.
For the first time, the American Heart Association Tuesday (07-23-01) advised postmenopausal women with heart disease not to go on hormone replacement therapy (HRT) and those without heart disease not to count on the treatment to protect them against it. Go here to read the entire article:!
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